Integrative network pharmacology and genomic analysis of esculin targeting PARP1 in cervical cancer: Insights from ADME profiling, molecular docking, and biomarker discovery
Protein-protein interaction and enrichment analyses supported PARP1's role in critical cancer-associated pathways, particularly in DNA damage response and chromatin remodelling, and efforts to develop a targeted cervical cancer therapy with esculin as a potential candidate are gaining traction.