Summary CFTR modulators like elexacaftor-tezacaftor-ivacaftor (ETI) improve morbidity in cystic fibrosis (CF), but their systemic effects on young children are not yet clear. We hypothesize that ETI has anti-inflammatory effects and reverse disease-associated molecular signatures in children with CF. This exploratory p...
H. Selvadurai, V. Han, Brooke A. Keating et al.· iScience· 0 citations
Summary Background Infection-triggered encephalopathy syndromes (ITES) are acute, para-infectious disorders that can cause disability or death. Recognition is increasingly important in viral pandemics, but clinical features and outcomes remain poorly understood. Methods PubMed search (inception to 6 March 2024) identif...
Michael Eyre, V. Han, Terrence Thomas et al.· EClinicalMedicine· 1 citation
Factor analysis revealed distinct 'cognitive and behavioural' and 'disinhibition and excitability' dimensions in the PASS items, which offers an alternative to adult scales, which may be difficult to use in children.
Priyanka Madaan, Suvasini Sharma, A. Easton et al.· Developmental Medicine & Chi...· 1 citation
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