Multiple sclerosis (MS) is a chronic, immune-mediated disorder of the central nervous system (CNS) characterised by inflammation, demyelination and neurodegeneration. The aetiology of MS is complex, arising from interactions among genetic susceptibility, environmental exposures and stochastic immune processes. Over the...
Jingni He, Nicholas B. Blackburn, V. Jokubaitis· Neurological Therapeutics· 0 citations
In this longitudinal study, mean sGFAP and sNfL levels remained stable over 9 years of sequential measurements during relapse-free periods, supporting the relapse-driven nature of NMOSD pathology.
P. Siriratnam, C. Dunai, Nkongho Egbe Franklyn et al.· Journal of Neurology Neurosu...· 0 citations
Key updates include expansion of dissemination in space to incorporate the optic nerve, integration of relapsing and progressive onset MS within a unified diagnostic framework, provision for diagnosis in selected asymptomatic individuals, dispensing with the requirement for dissemination of time in certain situations a...
P. Siriratnam, Mineesh Datta, Katherine A. Buzzard et al.· Autoimmunity Reviews· 0 citations
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