Novel antimicrobial peptides derived from Brevibacillus laterosporus DSM 25 targeting MurT ligase exhibit broad-spectrum activity against drug-resistant pathogens
The rapid rise of multidrug-resistant pathogens, poses a serious global threat, highlighting the need for new antimicrobial solutions. In this context, antimicrobial peptides (AMPs) have emerged as strong therapeutic candidates. Among potential targets, the MurT ligase, an ATP-dependent and highly conserved enzyme in G...