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Author

V. L. La Fazia

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Open access Oct 2026

Oral anticoagulation regimen after left atrial appendage occlusion in elderly atrial fibrillation patients with versus without cardiovascular comorbidities

Antithrombotic therapy is used after left atrial appendage occlusion (LAAO) to prevent device-related thrombosis (DRT) that could lead to stroke or transient ischemic attack (TIA). Ageing in atrial fibrillation (AF) as well as many age-associated comorbidities are known risk factor for stroke. Moreover, bleeding...

S. Mohanty, V. L. La Fazia, C. Gianni et al. · 0 citations
Open access Oct 2026

Long-term efficacy of pulsed-field ablation devices in real-world atrial fibrillation patients: a direct comparison between the Farapulse and the Affera ablation systems

Pulsed-field ablation (PFA) with its characteristic high tissue-selectivity, has recently emerged as a promising alternative to the conventional radiofrequency ablation for the management of atrial fibrillation (AF). This study evaluated the safety and efficacy of two systems using either a pentaspline or a latti...

S. Mohanty, V. L. La Fazia, C. Gianni et al. · 0 citations
Open access Oct 2026

Association of early recurrence with extended lesion sets beyond pulmonary veins in patients with atrial fibrillation undergoing pulsed-field ablation

Prior studies have reported a significant association between early (ER) and late recurrence following catheter ablation for atrial fibrillation (AF). However, there is limited data on the factors contributing to ER post-pulsed field ablation (PFA). We aimed to assess the link between extended ablation and ER in...

S. Mohanty, V. L. La Fazia, C. Gianni et al. · 0 citations
Sep 2026

Atrial Fibrillation Cycle Length Dynamics During Pulmonary Vein Isolation and Posterior Wall Pulsed Field Ablation.

BACKGROUND The benefit of additional left atrial posterior wall ablation (LAPWA), beyond pulmonary vein isolation (PVI), in persistent atrial fibrillation (PersAF) treatment remains controversial. OBJECTIVE We investigated whether signals recorded with a pentaspline pulsed field ablation (PFA) catheter can identify P...

Lorenzo Bianchini, M. Schiavone, A. Gasperetti et al. · 0 citations
Review Sep 2026

Left Atrial Appendage Closure: Past, Present, and Future

Left atrial appendage closure (LAAC) has emerged as an important alternative strategy for stroke prevention in patients with non-valvular atrial fibrillation (NVAF), particularly when long-term oral anticoagulation (OAC) is contraindicated or poorly tolerated. Initially developed as a surgical technique based on ligati...

E. Zito, Pamela Horton Embrey, V. L. La Fazia et al. · 0 citations

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