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V. Lorrain

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Open access Sep 2026

Homology-directed CRISPR-Cas9 correction of the KRT5 p.E475G mutation in human iPSC line from a patient with severe epidermolysis bullosa simplex.

The generation of the human induced pluripotent stem cell line MLi002-A-1 is reported, an isogenic control derived from patient-specific MLi002-A line carrying the KRT5 c.1424A > G (p.E475G) mutation, which enables mutation-specific studies and in vitro modeling of epidermolysis bullosa simplex.

Ana Trobec, V. Lorrain, Dusko Ilic et al. · 0 citations

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