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V. Manasa

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Open access Jul 2026

Synthesis and Biological Evaluation of Indole‐Benzene Sulfonamides as Carbonic Anhydrase II, IX, and XII Inhibitors

Human carbonic anhydrases (hCAs) are zinc‐bound enzymes that play a critical role in pH regulation and ion balance. Among them, isoforms hCA IX and XII are overexpressed in tumor hypoxia and are implicated in tumor progression. In this study, new indole‐benzenesulfonamide derivatives with hydrazide and amide linkers we...

V. Manasa, Sabesan Jayaprakash, Niccolò Paoletti et al. · 0 citations

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