Abstract We present a best‐practices protocol for targeted DNA methylation sequencing analysis that integrates both bisulfite‐ and enzymatic‐conversion approaches using Twist Bioscience technology. Building on established tools and vendor‐recommended workflows, this protocol provides a standardized, fully reproducible...
Vitória Rodrigues Guimarães Alves, Sheila T. Nagamatsu, V. Ota et al.· Current Protocols· 0 citations
BACKGROUND
The comprehensive elucidation of genomic relevance for mental disorder was, until recently, constrained by the limitations of microarrays or short-read sequencing (SRS). Long-read sequencing (LRS) provides access to complex classes of genetic variation and genomic architecture that are largely obscured in SR...
Bruno Takao Real Karia, V. Ota, Renato Polimanti et al.· Molecular Psychiatry· 0 citations
This most comprehensive assessment of epigenetic and brain age models across development is provided, evaluating how these models associate with chronological age and with each other, and how these associations change across development.
Marlene Staginnus, V. Baltramonaityte, I. Schuurmans et al.· bioRxiv· 0 citations
In this deeply phenotyped, admixed cohort, MDD-PRS showed relative diagnostic specificity and marked a more severe developmental course of depression, with NSSI associations contingent on MDD diagnosis, supporting the relative specificity, developmental utility, and cross-ancestry relevance of MDD-PRS.
M. Brañas, L. T. Ito, M. Croci et al.· Biological Psychiatry· 0 citations
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