Three generations of targeted therapies in chronic myeloid leukemia: Molecular advances, adverse effects, therapeutic challenges, and future perspectives
Introduction: The therapeutic landscape of chronic myeloid leukemia (CML) represents a paradigm of precision oncology, evolving across multiple generations of targeted breakpoint cluster region–Abelson murine leukemia viral oncogene homolog 1 tyrosine kinase inhibitors. As survival approaches that of the general popula...