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Review Sep 2026

In Silico Medicine: The Regulatory Gap in AI-Driven Drug Development

In silico medicine, which depends on computational modeling and simulation, is becoming more popular in drug discovery worldwide. Biomedical research is being rapidly transformed by Artificial Intelligence (AI), but there are risks associated with regulatory ambiguity. The integration of AI offers significant oppor...

S. Mutta, Naifa Faiz, T. N. et al. · 0 citations
Open access Sep 2026

Nitrosoamine Impurities: Current Status, Challenges and Future Perspectives

N-nitrosamine (NA) impurities have emerged as a critical safety concern in pharmaceutical manufacturing since the 2018 discovery of N-nitrosodimethylamine (NDMA) contamination in valsartan, which triggered global recalls and revealed similar issues in metformin, ranitidine, and rifampicin. Classified as Class 1 mutagen...

Sarupruthiya M, Jeevitha D, V. S et al. · 0 citations
Review Open access Sep 2026

The Role of Curcumin in Neurogenesis and Neuroprotection in Alzheimer’s disease: From Molecular Mechanisms to Clinical Evidence

Alzheimer's disease (AD) is the most common form of senile dementia worldwide and is a progressive and irreversible neurodegenerative disorder, which represents a huge socioeconomic burden on modern healthcare systems. The neuropathology of AD is characterised by a very complex, interconnected cascade of cellular event...

V. S, Sarupruthiya M, Jeevitha D et al. · 0 citations

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