Aug 2026
Design, synthesis, and structural characterization of covalent tetrahydroquinoline-based inhibitors of coronavirus 3CLpro.
These findings establish substituted tetrahydroquinolines as a viable scaffold for the development of broad-spectrum anticoronaviral agents and establish a promising in vivo safety profile.
A. A. Pronina, D. Shcherbakov, A. P. Sanchez-Pimentel et al.
· Bioorganic chemistry (Print) · 0 citations