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Open access Jul 2026

Structural basis for oligoclonal T cell recognition of a shared NRAS cancer neoantigen.

The structures explain how the NRASQ61K mutation rendered a self-antigen visible to T cells and provide stringent tests for computational modeling of TCR-peptide-MHC interactions relevant to cancer immunotherapy.

V. Sharma, D. T. Gallagher, S. Saravanakumar et al. · 0 citations

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