Summary Background Circadian disruption may affect metabolism through altered timing of sleep, activity, light exposure, hormonal rhythms, and food intake. However, its relationship with metabolic dysfunction-associated steatotic liver disease (MASLD), including fibrosis and cirrhosis remains unclear. To evaluate assoc...
Arunkumar Subramanian, R. A. Raja Ali, G. S. Dawe et al.· EClinicalMedicine· 0 citations
Aquaporin channels are the predominant fluid regulating channel found in the central nervous system (CNS) and plays a pivotal role in maintaining fluid and ion homeostasis, as well as regulating neuroinflammation, neurodegeneration, and blood-brain barrier (BBB) disruption. This protein is primarily located at astrocyt...
Balbir Singh, Shareen Singh, Souvik Banerjee et al.· International Journal of Neu...· 0 citations
RIOK3 is identified as a promising therapeutic target for PDAC, with Venetoclax, Conivaptan, Drospirenone, and Irinotecan as repurposable candidates for further research.
Kawthar Alhussieni, R. Othman, Tamilanban Thamaraikani et al.· Journal of Computer-Aided Mo...· 1 citation
A benzothiadiazole derivative is presented as a promising SERT‐modulating lead for AD, establishing a robust computational foundation for experimental validation and establishing a robust computational foundation for experimental validation.
