Aug 2026
Integrated in silico structural design & upstream expression optimization of an A7G mutant rh-G-CSF.
The novelty of the present research work lies in the incorporation of the structure-guided single residue modification and process optimization in one step, resulting in structurally validated A7G rhG-CSF and process optimization to 5 L scale in complex medium.
Sujani Thota, Gopichand Bitra, V. T C
· Preparative Biochemistry & B... · 0 citations