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Author

V. Toma

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Open access Jul 2026

Atherosclerotic-dose TMAO accentuates redox imbalances and motor dysfunctions in a MPTP mouse model of Parkinson’s disease

These findings carry clinical relevance in the context of Parkinson’s disease, suggesting that gut microbiome-derived metabolites may represent a pathological connection capable of increasing both cardiovascular risk and the progression of neurodegenerative disorders.

P. Panaitescu, Ioana Bâldea, V. Toma et al. · 0 citations
Open access Jul 2026

Fibroblast-Enhanced Tumour Microenvironment Signalling Promotes Adaptive Doxorubicin Tolerance in Heterotypic Melanoma Spheroids

These findings indicate that fibroblasts redirect chemotherapy responses toward a stress-adaptive, persister-like phenotype and establish fibroblast-containing 3D melanoma spheroids as a physiologically relevant platform for studying tumour microenvironment-mediated chemotherapy tolerance and stromal-tumour interaction...

Ilie-Ovidiu Pavel, G. Negrea, S. Mészáros et al. · 0 citations

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