Recognition of a "brain-heart axis" has grown substantially, highlighting the contribution of psychological stress on cardiovascular physiology and the development and progression of cardiovascular disease (CVD). This connection appears particularly consequential for individuals with established CVD. Laboratory-based m...
V. Vaccarino, Amit J. Shah, P. Mehta et al.· Stress· 0 citations
Heart failure (HF) affects 6.7 million people in the US and includes two major subtypes, HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF), with distinct genetic architectures. We meta-analyze genome-wide association studies (GWAS) of 38,781 HFrEF cases, 38,163 HFpEF cases, and 5...
Chang Liu, Qin Hui, Gregorio V. Linchangco et al.· Nature Communications· 0 citations
Background/Objectives: Human immunodeficiency virus (HIV) infection is characterized by chronic systemic inflammation. Antiretroviral therapy (ART) can reduce persistent inflammation, as measured by C-reactive protein (CRP). The CRP methylation risk score (MRSCRP) acts as proxy for plasma CRP, but longitudinal changes...
Yi-Jie Huang, Junyu Chen, A. Young et al.· Epigenomes· 0 citations
Poor sleep quality and short sleep duration were associated with higher population-level cardiometabolic risk factor burden, suggesting sleep quality may be a potential target for multimorbidity prevention.
K. Vashist, Laura Ward, Amit J. Shah et al.· Sleep Health· 0 citations
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