Author

V. Yudin

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Open access Aug 2026

Insights from GWAS, TWAS, and DEG analysis: CDKN2B-AS1, MAP3K4, and P2RX2-encoded P2X2 receptor identified as potential therapeutic targets for ischemic heart disease in Russian adults and long-living individuals

Background The purpose of this study was to investigate genetic risk factors associated with ischemic heart disease (IHD) in Russian adults, to develop prognostic PRS models for IHD risk stratification, and to gain a better understanding of molecular mechanisms underlying IHD through a transcriptome analysis. Materials...

Veronika Daniel, Наталья Георгиевна Романова, A. Mamchur et al. · Frontiers in Cardiovascular... · 0 citations

Open access Jul 2026

Congenital heart defects genetic architecture in a small cohort: an integrated approach to prioritizing variants

This study expands the understanding of the genetic landscape underlying congenital heart anomalies and emphasises the need for larger, deeply phenotyped cohorts to translate preliminary insights into clinically applicable predictors.

A. Korobeinikova, E. Petriaikina, D. Tychinin et al. · Frontiers in Cardiovascular... · 0 citations

Review Open access Jul 2026

Biomarkers of treatment response in rheumatoid arthritis: from conventional markers to tissue immunophenotype

It is concluded that precision medicine in RA will require integrated biomarker panels combining clinical, pharmacological, molecular, and synovial tissue data, and the development of scalable, externally validated, and clinically interpretable models capable of assigning synovial endotypes and supporting mechanism-bas...

N. A. Batashkov, E. Gerasimova, D. Gerasimova et al. · Frontiers in Immunology · 0 citations