Open access
Jul 2026
The CD83 axis between Tregs and CCR7+ dendritic cells governs anti-tumor immune responses 2309951
This study demonstrates that the ablation of interaction of CD83 molecule between CCR7+DC and Tregs results in increased anti-tumor immune response, and identifies CD83 as a cellular and molecular checkpoint that restrains T cell responses and can be targeted therapeutically.
Ruparoshni Jayabalan, Ricardo Gonzalez-Delgado, Luis A. Castillo Montanez et al.
· Journal of Immunology · 0 citations