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Valéria Bresolin da Rosa

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Open access Sep 2026

Antiglioma Effects of Monepantel: Roles of Autophagy and Endoplasmic Reticulum Stress

Background/Objective: New therapeutic targets are urgently needed for glioblastoma, the most aggressive primary brain tumor in adults. Monepantel (MPL), a repurposed anthelmintic, is thought to act in cancer cells through ATF4-mediated endoplasmic reticulum (ER) stress that inhibits mTORC1, but this axis had not been e...

Nicole Sartori-Borin, Giany Padão, Valéria Bresolin da Rosa et al. · 0 citations

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