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Valorie D Myhre

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Cdc42 Inhibition in G93A-hSOD1 Amyotrophic Lateral Sclerosis: In Vitro and In Vivo Studies

It is identified that Cdc42 activation in disease-state neurons may be deleterious and Cdc42 inhibitors, ZCL367 and high-dose ZCL279, appear to be neuroprotective against the selective degeneration of α-MNs in the ventral horn of G93A-hSOD1 transgenic (Tg) mice.

Valorie D Myhre · 0 citations