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Author

Vanja Kalajdzic

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Open access Sep 2026

Development of G Protein-Coupled Receptor 183 Benzimidazole Antagonists Utilizing a Core-Hopping Approach

G protein-coupled receptor 183 (GPR183, EBI2) has emerged as a promising therapeutic target for neuropathic pain due to its role in neuroinflammatory signaling. Previously, our group identified SAE-14 as a potent GPR183 antagonist and lead scaffold for analgesic development. To further explore the structural requiremen...

Angelina Ellis, Israel I. Olayide, Vanja Kalajdzic et al. · 0 citations

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