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Author

Vasudevan Ramachandran

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Review Open access Aug 2026

Nano formulations of quercetin for ocular delivery

Quercetin (QUE), a bioactive flavonoid with potent antioxidant, anti‑inflammatory, and neuroprotective properties, has emerged as a promising therapeutic candidate for age‑related macular degeneration, diabetic retinopathy, cataracts, glaucoma, dry eye disease, and allergic conjunctivitis. Its therapeutic effects are p...

M. N. Salleh, Henkie Isahwan Ahmad Mulyadi Lai, Mohd Aizat Zain et al. · 0 citations
Review Open access Aug 2026

KRAS mutations as architects of the tumor immune microenvironment: implications for combination therapies

The recent approval of covalent KRAS G12C inhibitors, sotorasib and adagrasib, has revealed that targeted KRAS blockade can remodel the TME toward an immunostimulatory state, providing a mechanistic rationale for combining KRAS-directed agents with immune checkpoint blockade, STING agonists, and neoantigen vaccines.

Vasudevan Ramachandran, H. L. Koyou, Siddarth Raajasekar et al. · 0 citations

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