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Author

Víctor Urbiola-Salvador

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Open access Oct 2026

Integrated spatial and single-cell transcriptomics uncover IFI6⁺ regulatory T-cells and SPP1⁺ macrophages immunosuppressive niches in colorectal cancer.

BACKGROUND In colorectal cancer (CRC), tumor-immune interactions are critical drivers of tumorigenesis, immune evasion, and therapeutic response. Therefore, a deeper spatially resolved understanding of these interactions is urgently needed. METHODS Spatial transcriptomics (ST) of CRC and matched normal samples was us...

Dominika Miroszewska, Shi-Yang Song, Víctor Urbiola-Salvador et al. · 0 citations

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