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Author

Victoria A. Ektnitphong

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Open access Sep 2026

SMURF2 inhibits autophagic control of Mycobacterium tuberculosis in macrophages.

Autophagy is a critical host defense mechanism that restricts intracellular pathogens such as Mycobacterium tuberculosis (Mtb). A key step in this process is the ubiquitination of Mtb or Mtb-associated structures. The E3 ligase SMURF1 catalyzes K48-linked ubiquitination, promoting bacterial clearance. However, the func...

Priscila C. Campos, Kathryn C. Rahlwes, Victoria A. Ektnitphong et al. · 0 citations
Open access Aug 2026

Sorting nexin 5 deficiency impairs MHC class II antigen presentation and inflammatory responses during tuberculosis

This work identifies SNX5 as a regulator of MHC class II antigen presentation that influences inflammatory outcomes during pulmonary Mtb infection and identifies SNX5 as a regulator of MHC class II antigen presentation that influences inflammatory outcomes during pulmonary Mtb infection.

Beatriz R. S. Dias, Kubra F. Naqvi, Victoria A. Ektnitphong et al. · 0 citations

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