Open access
Jul 2026
Mutational bias shapes protein evolution across RNA viruses
A nearly neutral framework that translates nucleotide mutational spectra into expected amino acid substitution patterns and equilibrium amino acid compositions indicates that departures from the nearly neutral baseline provide a quantitative proxy for purifying and positive selection.
B. Efimenko, Alexander Voronka, Victoriya Skripskaya et al.
· bioRxiv · 1 citation