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Author

Vijay A. Rathinam

1 paper indexed here

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Open access Aug 2026

Unanchored ubiquitin chains promote the non-canonical inflammasome via UBXN1

The non-canonical caspase-4 inflammasome is a crucial anti-bacterial immune mechanism, yet, when dysregulated, may contribute to sepsis pathogenesis. Its regulation is heavily reliant on transcriptional control of caspase-4 expression. However, posttranslational regulation of the caspase-4 inflammasome remains poorly u...

Duo-Meng Yang, Jason G. Cahoon, T. Geng et al. · 0 citations

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