Vijay Rangachari

Leveraging Supramolecular Polymers to Induce the Targeted Protein Degradation of α-Synuclein

This work focused on adding modularity and dynamic capability to this classical model by leveraging a multivalent macromolecular approach to TPD, where peptide amphiphiles were designed to self-assemble into high-aspect-ratio supramolecular nanofibers and present peptide epitopes on the surface of the fibers to target...