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Author

Vincent Lam

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Sep 2026

Abstract A048: TGFBR2 dysfunction rewires cell cycle, MAPK signaling, and migration in pancreatic cancer

The results suggest that PKT tumor aggressiveness may be attributed to preferential activation of cell cycle-associated programs over EMT-associated migration programs, and support G1/S cell cycle regulation as a potential vulnerability for combination therapy with KRASG12D inhibition or chemotherapy in TGFBR2-mutant o...

Vincent Lam, R. M. Walsh, Bailey A. Bye et al. · 0 citations

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