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Author

Vincent M. Christoffels

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Open access Jul 2026

TBX5-p.G125R postnatally deregulates pacemaker cardiomyocyte state and function.

It is concluded that alterations driven by TBX5-p.G125R in the transcriptional state of the postnatal sinus node contribute to sinus node dysfunction and atrial arrhythmias in adult Tbx5+/G125R mice, emphasizing the critical role of TBX5 in maintaining pacemaker cardiomyocyte state and function.

Lieve E. van der Maarel, Otto J. Mulleners, Laura H F Stoop et al. · 0 citations

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