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Author

Vincenzo Venditti

3 papers indexed here

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Review Open access Sep 2026

Beyond structures: solution NMR as the quantitative engine of integrated structural biology

Structural biology is moving beyond the determination of static molecular structures toward quantitative descriptions of biomolecular mechanisms. Modern questions increasingly focus on conformational heterogeneity, exchange kinetics, weak and transient interactions, allostery, disorder, assembly, and phase behavior. Th...

J. Purslow, Vincenzo Venditti · 0 citations
Open access Sep 2026

Integrating NMR and contact-response analysis reveals the allosteric network driving domain closure in Enzyme I

Significance Allosteric regulation enables proteins to transmit signals over long distances, but the mechanisms linking local ligand binding to global conformational changes remain difficult to resolve. Here, we combine NMR-based chemical shift covariance analysis with computational contact-response analysis to map the...

Aayushi Singh, Daniel Burns, Sergey L. Sedinkin et al. · 0 citations
Open access Jul 2026

1H, 15N, 13C backbone resonance assignment of Escherichia coli AlkB in complex with Zn(II) and α-ketoglutarate

The backbone 1H, 15N, 13C chemical shift assignment of E. coli AlkB in complex with Zn2+ and α-ketoglutarate is reported, allowing investigations of the protein structural dynamics anticipated to provide crucial insight regarding fundamental aspects in the recognition and enzyme regulation processes.

Sayan Das, J. Purslow, Kyle Malcom et al. · 0 citations

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