Open access
Aug 2026
Specific targeting of cancer cell mitochondria with a malaria drug improves pancreatic cancer outcome
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy. In this paper, we present DZ-ART1, a first-in-class, dual-function therapeutic. This innovative agent is composed of a tumor-targeting heptamethine carbocyanine dye conjugated to artemisinin (ART). Near-infrared imaging demonstrated precise tumor localizat...
Yan Ou, A. Lim, Ruo-Xiang Wang et al.
· Scientific Reports · 0 citations