Eco-friendly stability-indicating HPLC method development, validation, and LC-MS-based characterization of degradation products of the polar drug imeglimin.
Imeglimin (IMG) is a recently developed cyclic biguanide compound used for the management of hyperglycaemia. To comprehend the stability behavior of the polar drug IMG under various degradation environments, an HPLC method was developed, and the major degradation products (DPs) were characterized using mass-spectrometr...