Open access
Sep 2026
CRACD loss drives hypoxia-induced immune escape in gastric cancer
Mucinous gastric adenocarcinoma (MGC) is a distinct histologic subtype characterized by poor prognosis and limited responsiveness to chemotherapy and immunotherapy. CRACD, an actin polymerization regulator, is frequently inactivated in gastric cancer (GC), with enrichment in mucinous subtypes. We found that genetic...
Yoojeong Seo, Jinho Jang, Kyung-Pil Ko et al.
· Nature Communications · 0 citations