Through childhood and adolescence, profound changes to the physiology of individual neurons accompany large-scale network changes in the mammalian neocortex. These physiological changes are well understood in rodent models but far less is known in the human neocortex. Here we combine patch-clamp electrophysiology and s...
R. Kendrick, Jason K. Clark, Emmalyn S. P. Leonard et al.· bioRxiv· 0 citations
Supplemental Digital Content is Available in the Text. Placebo interventions in facial pain produce mild to moderate relief but rarely ≥75% improvement, suggesting ≥75% pain reductions after analgesic interventions are unlikely primarily placebo-driven.
S. Saluja, A. Kattaa, Bethany Shih et al.· PAIN Reports· 0 citations
An integrated framework for predicting and interpreting causal electrophysiological connectivity patterns between pairs of brain regions is developed, which maps human brain connectivity, bridging structural architecture, causal electrophysiological dynamics, and network-level communication.
S. Shailja, Dian Lyu, Gustavo Chau Loo Kung et al.· bioRxiv· 0 citations
OBJECTIVE
Epilepsy surgery in tuberous sclerosis complex (TSC) is underutilized but associated with improved seizure control and better neurocognitive outcomes. Here we focus on utilization of repeated surgeries to improve seizure control.
METHODS
We performed a retrospective chart review of 62 pediatric patients wit...
Alexandria Valdrighi, Kevin Pearsson, Jurriaan M. Peters et al.· Epilepsia· 0 citations
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