Vivek Phatale

Cell targeting peptide guided nanomedicine: a new paradigm in precision oncology for the management of non-small cell lung cancer.

Non-Small Cell Lung Cancer (NSCLC) remains a leading cause of cancer-related mortality worldwide owing to its high prevalence, metastatic potential, therapeutic resistance and poor survival outcomes. Effective management of NSCLC is hindered by the heterogeneous tumor microenvironment (TME), non-selective drug biodistr...

Intranasal Delivery of Piceatannol-Loaded Liposomes for Glioblastoma Management: Formulation Optimization, In Vitro, Ex Vivo, In Ovo and LC-MS/MS- Based In Vivo Pharmacokinetic and Brain Distribution Assessment

Unlocking exosome potential: Comprehensive review on diagnostic, prognostic and therapeutic approaches in melanoma.

Melanoma is one of the most lethal and aggressive forms of skin malignancies, which characterized by a high mutational burden, rapid metastatic dissemination and development of resistance to targeted and conventional therapies. Increasing interest in site-specific delivery has led to tailored therapeutic delivery mecha...

Intranasal Pacritinib-loaded nanoemulsion for Glioblastoma management: In Vitro, ex Vivo, 3D spheroid and In vivo brain biodistribution studies.

It can be concluded that PAC-NE is a non-invasive delivery system which shows promising results for better brain delivery thereby supporting the clinical translation of PAC for GBM therapy.