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Author

Vlad Costache

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Open access Aug 2026

Spatiotemporal regulation of LGN/NuMA and astral microtubules generate mirror symmetric spindle rotations

The positioning of the mitotic spindle controls the size, content, and position of daughter cells within embryos and tissues. A major spindle positioning mechanism is “cortical pulling” whereby the membrane-bound complex LGN/NuMA/Dynein captures astral microtubules and pulls centrosomes toward the cell cortex. Cytoplas...

Janet Chenevert, Anne Rosfelter, Daniel Gonzalez-Suarez et al. · 0 citations

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