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Vyshnavi Daggubati

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Open access Sep 2026

Integrative Single-Cell, Spatial, and Bulk Transcriptomics Characterizes an Outcome-Associated, Spatially Organized Mesenchymal Program in IDH-Mutant Glioma

IDH-mutant gliomas show variable clinical behavior that may reflect transcriptional programs organized within tumor tissue. We evaluated two curated expression scores: a differentiation-loss/Stem-NPC score (Axis1) and a mesenchymal–hypoxia score (Axis2). Public single-cell RNA-sequencing data were used to characterize...

Kesavi HimaBindhu Vuyyuru, Vyshnavi Daggubati, Abraham Peele Karlapudi et al. · 0 citations

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