Author

W. Aboulthana

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Open access Nov 2026

Design, Synthesis, and Biological Evaluation of Molecular Hybrids Incorporating Coumarin‐Pyrazole‐Linked Indolinone Derivatives With Antioxidant and Anti‐Alzheimer Properties

ABSTRACT The increase in global life expectancy has resulted in a significant rise in the occurrence of Alzheimer's disease (AD), making it a critical public health burden. Therefore, there is an urgent need to create effective methods to prevent or slow down the progression of the disease. In this regard, fifteen prev...

Ahmed Sabt, W. Aboulthana, Abdulrahman M. Saleh et al. · Chemistry and Biodiversity · 0 citations

Open access 2026

Synthesis and therapeutic evaluation of isatin-linked pyrazole motif derivatives

Multi-target drugs possess significant therapeutic potential for the therapy of complex diseases and drug-resistant conditions. Based on this fact, isatin-pyrazole derivatives, namely, 5-substituted isatin-pyrazole derivatives 7a-d and N-alkyl isatin-pyrazole derivatives 9a-d, were prepared by merging the pyrazole moti...

Mohamed A. Al-Omar, H. Alkahtani, M. A. Bhat et al. · Bulletin of the Chemical Soc... · 0 citations

Open access Aug 2026

Development of new imidazopyridine-based chalcones hybrids as potent antidiabetic and antioxidant agents: synthesis, in silico and in vitro evaluation

A novel series of six imidazopyridine-based chalcone hybrids is synthesized and evaluated their in vitro biological activities, including total antioxidant capacity, iron-reducing power, and radical scavenging (DPPH, ABTS, NO), as well as antidiabetic potential against α-amylase, α-glucosidase, and aldose reductase.

Hanan Abdelmawgoud Atia, Aladdin M. Srour, Hanaa Farag et al. · Scientific Reports · 0 citations