Author

W. Backes

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Open access Aug 2026

Disentangling MRI-derived blood–brain barrier leakage into vascular permeability and surface area

In neurovascular and neurodegenerative diseases, blood–brain barrier (BBB) disruption can be subtle and diffuse, and MRI-derived measures are confounded by microvascular architecture. Therefore, we aimed to disentangle the MRI-derived blood–brain barrier leakage rate (Ki) into intrinsic vascular permeability (P) and su...

Damon Verstappen, J. D. de Jong, P. Voorter et al. · Journal of Cerebral Blood Fl... · 0 citations

Open access Sep 2026

Volumetric and functional connectivity alterations of the thalamus and thalamic nuclei groups in drug-resistant focal epilepsy: A 7T MRI study.

PURPOSE Through its global and extensive connections with multiple brain structures, the thalamus can play an important role in seizure propagation. This study investigated volumetric and functional connectivity alterations of the thalamus and more specifically the thalamic nuclei subgroups using 7T MRI in patients wit...

D. Uher, L. Vermeer, J. Jansen et al. · Neuroradiology · 0 citations

Open access Jul 2026

Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI

BACKGROUND: The Fazekas score is widely used to grade white matter hyperintensities (WMHs) in cerebral small vessel disease, yet the equivalent volume of each grade is unclear. We quantified the correspondence between Fazekas scores and WMH volume, normalized ratios, and derived conversion equations across populations....

Yuyuan Xu, Francesca M. Chappell, M. V. Valdés Hernández et al. · Stroke · 0 citations