Jul 2026
Spatial Profiling Links Metabolic Reprogramming and Stromal Fibroblasts to PD-L1-Discordant NSCLC Responses 2309385
Findings establish meCAF-VEGFA-tumor crosstalk as a therapeutic vulnerability and support spatially-resolved tumor-stroma profiling as a prognostic tool beyond PD-L1 for predicting ICI responses.
Yongjae Kim, Seong-Eun Kim, Bokyung Ann et al.
· Journal of Immunology · 0 citations