Open access
Oct 2026
Impact of age on implementation and tolerability of guideline-directed medical therapy in heart failure with reduced ejection fraction
The need for improved implementation strategies to optimize guideline-directed therapy and dosing levels in the ageing HFrEF population is highlighted, with use of GDMT associated with better clinical outcomes, also among older patients.
J. J. N. Krabbe, M. I. Wilde, W. L. Verloop et al.
· European Heart Journal · 0 citations