Author

W. Labaki

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Open access Sep 2026

One-year progression of CT emphysema subtypes predict lung function decline: SPIROMICS.

One-year progression of CT emphysema subtypes predicted accelerated FEV₁ decline, supporting their potential use as intermediate endpoints in COPD trials and evaluating associations between one-year QCT measure changes and FEV₁ decline from visits two through five.

Emilia A. Hermann, E. Hoffman, Elsa D. Angelini et al. · American Journal of Respirat... · 0 citations

Sep 2026

Systemic Platelet Activation and Respiratory Exacerbations, Pulmonary Symptoms, and Mortality among Current and Former Smokers in SPIROMICS.

RATIONALE Platelet activation is elevated in chronic obstructive pulmonary disease (COPD) and associated with self-reported respiratory symptoms. Observational studies link the antiplatelet drug aspirin to lower exacerbation rates and fewer symptoms. However, it is unknown if platelet activation predicts incident respi...

A. Fawzy, N. Hansel, N. Putcha et al. · Annals of the American Thora... · 0 citations

Open access Sep 2026

Clinician-Perceived Barriers and Facilitators for Initiation and Management of Noninvasive Ventilation Among Patients With Chronic Hypercapnia From COPD: A Qualitative Study.

Background Long-term non-invasive ventilation (NIV) improves survival and re-admission risk for patients with chronic hypercapnia from chronic obstructive pulmonary disease (COPD). However, outpatient NIV prescription remains low. Methods We conducted a qualitative study using semi-structured interviews with pulmonar...

P. J. Checinski, K. Byrd, W. Labaki et al. · Chronic obstructive pulmonar... · 0 citations