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Author

W. M. Kast

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Sep 2026

The mRNA-Based Therapeutic Vaccine NTX250 Induces Potent Antitumor Immunity in HPV-Driven Cancers.

Human papillomavirus (HPV) plays a pivotal role in various malignancies, including cervical, anogenital, head, and neck cancers. Despite the availability of highly effective prophylactic vaccines, many individuals remain susceptible to HPV-driven cancers due to barriers such as limited vaccine access, lack of awareness...

Meredith Leong, Wei-Qun Liu, Nicole C. Fay et al. · 0 citations
Jul 2026

Identifying and reprogramming softness-driven cancer stem-like cells overcomes CAR-T cell resistance in solid tumours.

To render these resistant cells targetable, the mechano-recorder is rewired into a mechano-reprogrammer by replacing the fluorescent output with the clinically validated antigen CD19, enabling softness-responsive cells to be recognized by CD19-directed T cells.

Yunjia Qu, Yuxuan Wang, Linshan Zhu et al. · 2 citations

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