Population diversity and accelerated mutation drive anaerobic bacterial adaptation during long-term solvent stress
ABSTRACT Experimental evolution can uncover general mechanisms by which microorganisms adapt to environmental stress. Here, we investigate evolutionary trajectories of the anaerobic, lignocellulose-fermenting bacterium Lachnoclostridium phytofermentans ISDg (family Lachnospiraceae) during >2,000 generations of automate...