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Oct 2026

Delirium after Aortic Arch Surgery with Hypothermic Circulatory Arrest: Clinical and Neuroimaging Insights from the GOT ICE Randomized Trial.

BACKGROUND Postoperative delirium (POD) is a complication of arch surgery with hypothermic circulatory arrest (HCA) and may contribute to long-term cognitive decline, but prospective data are limited. We examined its incidence, predictors, and neurocognitive and neuroimaging correlates. METHODS The Cognitive Effects...

G. C. Hughes, Jeffrey N. Browndyke, Edward P. Chen et al. · 0 citations
Review Open access Sep 2026

Thoracic aortic disease: prognostic role of gene variants and polygenic risk scores.

P/LP HTAAD gene variants confer a substantial population-level increased risk of TAAD, suggesting that integrating monogenic and polygenic risks has the potential to enhance patient risk stratification and treatment.

J. DePaolo, D. Smelser, Dong-Chuan Guo et al. · 0 citations

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