Author

Wei-Xian Yang

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Open access Oct 2026

Lipoprotein(a) and Risk Stratification for Atherosclerotic Cardiovascular Disease Across the Cardiovascular-Kidney-Metabolic Continuum.

BACKGROUND Lp(a) (lipoprotein(a)) is an established risk factor for atherosclerotic cardiovascular disease (ASCVD), but its prognostic relevance across the cardiovascular-kidney-metabolic (CKM) continuum remains uncertain. We examined whether Lp(a) was associated with incident ASCVD across CKM stages and whether it pro...

Yan-Wen Fang, Xu-Yan Pei, Si-Zhuang Huang et al. · Journal of the American Hear... · 0 citations

Open access Oct 2026

The TyG index and cardiovascular mortality in type 2 diabetes: a mediation analysis of renal function in two prospective cohorts

The triglyceride-glucose index (TyG), a marker of insulin resistance, has been established as a predictor of cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). However, the underlying mechanisms linking TyG to cardiovascular disease remain unclear, leaving intervention targets ambiguous. Given...

Y. Liu, J. Yuan, S. Wu et al. · European Heart Journal · 0 citations

Open access Sep 2026

Single-Cell Transcriptomics Reveals the Immune Pathogenesis of Isolated Coronary Arteritis Presenting as Refractory In-Stent Restenosis.

The aim of the present study was to elucidate the cellular and molecular mechanisms underlying refractory recurrent in-stent restenosis (RISR), thereby facilitating the identification of potential therapeutic targets. Coronary blood samples were obtained from culprit lesions of patients with RISR and non-ISR controls a...

Miao Yu, Yu Jiang, Ji Huang et al. · JACC: Basic to Translational... · 1 citation