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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Wa Xian

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2 papers indexed here

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Sep 2026

Abstract A040: Intratumor stem cell repertoire in pancreatic cancer

Metastatic pancreatic ductal adenocarcinoma (PDAC) is difficult to manage, has an overall survival of approximately nine months, and will soon be the second leading cause of death among cancers. The poor outcome of PDAC patients has been attributed, in part, to a pattern of intratumor heterogeneity reflected in the g...

Wa Xian, Frank Mckeon, J. Ajani et al. · 0 citations
Jul 2026

Abstract A017: FAP-Activated Prodrugs Target Cancer Stem Cells in Esophageal Adenocarcinoma

FAP-activated ponatinib prodrugs achieve selective, TME-compartmentalized delivery with substantially reduced systemic exposure and, when combined with the IAP antagonist 7532N as the TP101 regimen, provide a precision, stem cell-selective synthetic lethal strategy for this rare and aggressive malignancy.

Frank Mckeon, Wa Xian, Ruiwen Zhang et al. · 0 citations

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