Open access
Sep 2026
Impaired Regulated Exocytosis and GLUT4 Trafficking in Dysferlin-Deficient Human Myoblasts: A Pilot Study
Background/Objectives: Dysferlinopathies are inherited muscular dystrophies caused by DYSF mutations that lead to progressive muscle degeneration. Proteomic analyses of patient muscle reveal altered abundance of proteins involved in regulated exocytosis and energy metabolism, reflecting complex molecular remodeling wit...
María José Guerra-Fernández, Walter Vásquez, Hugo Almarza-Salazar et al.
· Biomedicines · 0 citations