Author

Wanchao Liu

3 papers indexed here

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Aug 2026

Neuroprotective effect of miR-519a-3p downregulation against sevoflurane-induced cognitive dysfunction via regulating ESR1.

BACKGROUND Sevoflurane (Sevo) is widely applied in clinical anesthesia practice, and exposure to this agent has been linked to cognitive impairment. PURPOSE This study aimed to explore how microRNA-519a-3p (miR-519a-3p) contributes to Sevo-induced cognitive impairment and the molecular mechanisms involved. METHODS...

Weiwei Lin, Dan Yu, Xiating Shi et al. · Toxicology and Applied Pharm... · 1 citation

Open access Jan 2026

Integrating Serum Lipid Biomarkers Into Machine Learning for the Differential Diagnosis of Breast Nodules

Objective To develop and validate an interpretable machine learning (ML) model for predicting malignant risk in patients with breast nodules using serum lipid biomarkers. Methods This retrospective study included 899 patients with breast nodules (236 malignant) admitted between March 2022 and December 2024. Patients we...

Longmei Chen, Yuzhen Du, Wan-Chao Liu · The Breast Journal · 0 citations

Case report Open access Jul 2026

Therapy-related myelodysplastic syndrome rapidly evolving to acute myeloid leukemia following CAR-T cell therapy in a patient with refractory diffuse large B-cell lymphoma: a case report

Background Persistent cytopenia following chimeric antigen receptor T-cell (CAR-T) therapy is an increasingly recognized complication in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). While most cases stem from transient, immune-mediated mechanisms or depleted bone marrow reserves, secondar...

Longmei Chen, Wanchao Liu · Frontiers in Oncology · 0 citations