CCKBR (Gastrin Receptor) as a Theranostic Target in Oncology: Biological Rationale, Diagnostic Imaging, and Next-Generation Peptide-Based Drug Development
Cholecystokinin B receptor (CCKBR) is a promising theranostic target because of its overexpression in several malignancies, including medullary thyroid carcinoma, small-cell lung cancer, gastric cancer, and pancreatic cancer. Its high-affinity ligand binding and efficient receptor-mediated internalization provide a str...